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Updated on August 4, 2023
7 min read

Is it Safe to Combine Delta-8 with Alcohol?

Kelly Brown
Dr P. E. Pancoast, MD
Written by 
8 Sources Cited
Kelly Brown
Written by 
8 Sources Cited

What is Delta-8 THC?

Delta-8 THC (Tetrahydrocannabinol) is a synthetic version of Delta-9, making its chemical structure different. Both are psychoactive compounds found in the Cannabis plant.

Delta-8 produces a ‘high’ similar to other THC-containing compounds or THC analogs. Manufacturers make it through a method called isomerization, converting cannabidiol (CBD) into Delta-8.1

Is Delta-8 THC Legal?

The 2018 Farm Bill made industrial hemp products legal if they contain less than 0.3 percent Delta-9. Delta-8 products have less than 0.3 percent of Delta-9 THC, making it legal at the federal level.

Despite the federal legal status of Delta-8, some states still prohibit the sale of products containing any amount of Delta-8 or Delta-9. People undergoing drug tests will usually test positive for THC when taking Delta-8.


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Effects of Delta-8 THC On the Body

Many people experience a high when using Delta-8, just as they would with Delta-9. Depending on the dosage, it may be milder and lack the anxiety and paranoia some experience with Delta-9.

Other side effects of Delta-8 similar to Delta-9 include:

  • Dry mouth
  • Red eyes
  • Rapid heart rate
  • Memory loss
  • Slow reaction time

Psychoactive Effects of Delta-8

Many users report feeling “less trippy” when using Delta-8. However, it changes how your brain responds to certain stimuli.

The psychoactive effects of Delta-8 include:

  • Behavioral changes
  • Mood changes
  • Changes in awareness
  • Changes in how you feel
  • Altered thoughts

For many people, the high from Delta-8 is more clear-headed and body-focused.

Delta-8’s Impact on Physical Health 

Although some consider Delta-8 to have more mild effects than Delta-9, it can still produce the following side effects:

  • Lethargy
  • Slurred speech
  • Uncoordinated movement
  • Increased heart rate
  • Slowed heart rate
  • Low blood pressure
  • Sedation
  • Difficulty breathing
  • Tremors
  • Dizziness
  • Coma

The risk of harmful side effects increases based on the amount of Delta-8 consumed. Eating large amounts of 8 can cause vomiting.

Can You Mix Delta-8 THC and Alcohol?

You can mix Delta-8 and alcohol, but it’s risky. Drinking alcohol while using cannabis-based products is known as cross-fading.

Alcohol and THC enhance dopamine, a neurotransmitter in the brain. It creates a feeling of euphoria.

While some people don’t notice much difference in their highs, others experience unpleasant side effects. If you’ve never mixed alcohol and THC, knowing how your body will react beforehand is impossible.


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What Happens When You Mix Delta-8 and Alcohol?

Many people don’t feel any different mixing alcohol and Delta-8 than they do if they drink while using regular marijuana. The results vary from person to person.

Some find that taking Delta-8 and drinking increases both substances’ euphoric effects, while others report feeling the same as if they’d only used THC or alcohol.

Does Mixing Delta-8 and Alcohol Increase THC Blood Levels?

No definitive studies indicate that THC blood levels increase when you combine cannabis with alcohol.

A 2012 study showed that THC levels in the blood are higher when people ingest THC before consuming alcohol than those who used cannabis alone.4 Meanwhile, a 2013 study showed that consuming alcohol before ingesting marijuana did not influence the amount of THC in the blood.6


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Potential Risks of Combining Delta-8 THC and Alcohol

Mixing substances, or crossfading, produces unpredictable results, but some have been documented as common outcomes.

The side effects of combining Delta-8 THC and alcohol include:

  • Feelings of spinning (“greening out”)
  • Dehydration
  • Dizziness
  • Sweating
  • Increased THC levels in the blood
  • Increased risk of overdose (on both substances)

Remember, alcohol usage with any other drug is always risky and could be a sign of substance misuse.

Can You Overdose on Delta-8 and Alcohol?

There’s a risk of overdosing when combining alcohol and THC because it can slow down alcohol absorption. It prevents you from feeling drunk and could lead to someone drinking more than their body can handle.

However, a study found that these two substances likely don’t directly influence each’s access to the blood and brain. Mixing them did not slow alcohol absorption or increase THC absorption.6

Regardless, it’s essential to remember that crossfading puts you at greater risk of health problems, including alcohol addiction. With impaired judgment, you have less self-control and self-awareness, leading to a higher potential for habit-forming behaviors in the long-term.

Can Delta-8 THC Help with Alcohol Withdrawal?

Some people believe that using marijuana or Delta-8 can help them decrease their alcohol consumption. There is no conclusive research that proves this to be the case. Because Delta-8 is a newer product, there’s even less known about whether or not it can be used for managing alcohol withdrawal.

Can Delta-8 THC Help Reduce Alcohol Intake?

No. But the opposite may be true. Mixing marijuana products and alcohol can lead to drinking more than usual to achieve the same effect. If someone drinks more than their body can handle, it puts them at risk of alcohol poisoning.

Is Delta-8 More Dangerous Than Delta-9?

Although Delta-8 might seem less risky to use than Delta-9, this isn’t necessarily true. Even if they are synthetically produced, Delta-8 products have no regulatory oversight. This means the manufacturer’s claims about a product could be incomplete or misleading.

Delta-8 products could also put you at risk of:

  • Headaches
  • Lightheadedness and dizziness
  • Drowsiness
  • Fatigue
  • Nausea and vomiting
  • Disorientation
  • Hallucinations
  • Increased appetite2

Can You Combine Delta-8 and Delta-9?

Delta-9 is naturally more potent than Delta-8, but both produce similar effects. Although there are no known adverse effects or benefits of mixing Delta-8 and Delta-9, the outcome of combining them varies based on how much of each you take.

Both Delta-8 and Delta-9 bind to CB-1 receptors in the body. It is a receptor in the brain and central nervous system responsible for intoxication. Because the two substances ‘fight’ for the same receptors, combining them may affect the absorption of one or both of them.

Ultimately, your body’s reaction to combining Delta-8 and Delta-9 comes down to specific variables when you ingest the substances. These include:

  • Dosage
  • THC Tolerance
  • Body weight
  • Other biological factors

It’s also important to consider the risks of increasing the substance’s dosage. For example, someone who takes 10 mg of Delta-9 and adds 10 mg of Delta-8 will experience more potent effects than usual.

While combining THC products usually isn’t a serious problem, taking too much THC can result in unpleasant side effects such as increased anxiety and paranoia.

Common Questions on Delta-8 and Alcohol

Does Delta-8 THC Give You a Hangover?

No. The usual effects someone feels after drinking (headache, nausea, fatigue, etc.) rarely occur when someone consumes Delta-8 or any THC product.

However, you can have these symptoms if you consume high amounts of THC or mix THC with alcohol or other substances.

How Long Does Delta-8 THC Stay In Your System?

Generally, THC stays in your system for 2 to 30 days. However, some variables affect how long the substance remains. These variables include:

  • Frequency of use
  • Age
  • Consumption method
  • Metabolic rate
  • Quantity of dose
  • Other medications and supplements used

What Else Should You Avoid Mixing With Delta-8 THC?

In addition to alcohol, you should avoid mixing Delta-8 with other substances, such as:

  • Antidepressants
  • Benzodiazepines
  • Blood pressure medication
  • Blood sugar medications
  • Immunosuppressants
  • Opioids

These medications rely on an enzyme that THC might suppress. This means they are likely to take longer to take effect if THC is used simultaneously.


Delta-8 is a manufactured product containing THC. It induces effects similar to other THC products but tends to be less potent. Many of Delta-8’s side effects are the same as with similar products.

Some consider Delta-8 a safer form of THC. However, there’s no governmental regulation of these products. They might also produce unpredictable outcomes, even in a low dose.

As with any drug, it’s best not to mix it with other substances like alcohol or other forms of medication. It’s always best to consult with medical professionals if you have questions or concerns about how consuming THC could affect you or any ongoing treatment you are under.

If you believe you’re struggling with using Delta-8, THC, or any other substance, treatment options are available.

Updated on August 4, 2023
8 sources cited
Updated on August 4, 2023
All Alcoholrehabhelp content is medically reviewed or fact checked to ensure as much factual accuracy as possible.

We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies.
  1. Holler et al. “Isomerization of Delta-9-THC to Delta-8-THC When Tested as Trifluoroacetyl-, Pentafluoropropionyl-, or Heptafluorobutyryl- Derivatives.” Journal of Mass Spectrometry, 2008.

  2. Marijuana.” Mayo Clinic, 2017

  3. Downey et al. “The Effects of Cannabis and Alcohol on Simulated Driving: Influences of Dose and Experience.” Accident Analysis & Prevention, 2013.

  4.   Yurasek et al. “Co-Use of Alcohol and Cannabis: A Review.” Current Addiction Reports, 2017.

  5. Hartman et al. “Controlled Cannabis Vaporizer Administration: Blood and Plasma Cannabinoids with and without Alcohol.” Clinical Chemistry, 2015.

  6. Wenk, G.W. “How Do Marijuana and Alcohol Interact inside Your Brain?” Psychology Today, 2019.

  7. Lukas et al. “Marihuana Attenuates the Rise in Plasma Ethanol Levels in Human Subjects.” Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology, 1992. 

  8. Know the Risks of Marijuana.” Substance Abuse and Mental Health Services Administration (SAMHSA), 2023.

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All content created by Alcohol Rehab Help is sourced from current scientific research and fact-checked by an addiction counseling expert. However, the information provided by Alcohol Rehab Help is not a substitute for professional treatment advice.
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